Welcome to Research Studies with Working-Age Adults
This page provides a list of all studies which are currently open to new participants.
All research listed here has received full Ethical Review and Approval by the national Health Research Authority (HRA). Each study provides a link to the HRA National Study Record confirming its approval status.
Key to Use
The Blue box gives the short name of the study, so it is easy to remember.
The Orange box states whether the study is national (funded research), local (small-scale and internal to the Trust) or Educational (such as Student, PhD or MSc research).
The Green box states what kind of study the project is. It may be a Drug Trial, A Therapy study, A Trial which involves testing an educational or support package, or an Observational study where people are given questionnaires or are interviewed with no change to clinical care.
The Purple box states whether the study is Open to anyone to meets the criteria listed and who wishes to take part, or Restricted to certain groups of people (such as those in specific care services or certain schools or colleges).
Purpose of study: National Centre for Mental Health (NCMH) The long-term vision is to improve diagnosis and to develop and evaluate ways of preventing the onset, and improving the treatment and management of mental disorders through obtaining information about participants' mental and physical health, lifestyle, and background, as well as blood samples
Who can be involved?
•Aged 18 or over
•Diagnosis of either: Schizophrenia, Schizoaffective Disorder, Bipolar Affective Disorder, PTSD, Post-Partum Psychosis
•Willing to provide a blood sample
Lead Researcher and Organisation: Professor Ian Jones, Cardiff University
Contact if you are interested in learning more: firstname.lastname@example.org (Norfolk and Suffolk only)https://www.ncmh.info/ (National Details)
Purpose of study: Tailoring evidence-based psychological therapY for People with common mental disorder including Psychotic Experiences Work Package 3d (TYPPEX): a feasibility study
•Referred to the Wellbeing service
•Presence of psychotic experiences
•Lead Researcher and Organisation: Professor Jesus Perez, Cambridgeshire and Peterborough NHS Foundation Trust
Contact if you are interested in learning more: email@example.com (Norfolk and Suffolk only)
Purpose/Long-title of study: EFFIP (E-support for Families and Friends of Individuals affected by Psychosis): A randomised controlled trial of a co-produced online intervention for carers
•Carers need to have at least weekly contact with the cared-for person
•Have regular access to the internet;
Lead Researcher and Organisation: Dr Jacqueline Sin, University of London
Contact if you are interested in learning more: firstname.lastname@example.org (Norfolk and Suffolk only)http://cope-support.org/get-involved/ (National Details)
Further Details: National Study Record
Purpose/Long-title of study: National Confidential Inquiry into Suicide and Homicide by People with Mental Illness
Nature of study: National data-set analysis
Lead Researcher and Organisation: Professor Louis Appleby, University of Manchester
Contact if you are interested in learning more: https://sites.manchester.ac.uk/ncish/ (National Details)
Purpose/Long-title of study: Interleukin 6 Inhibition in Inflamed Depression: The Insight StudyResearch suggests inflammation may cause depression, but precise mechanisms are unknown. The main objectives of this study are to test whether interleukin 6 (IL-6), a pro-inflammatory protein, contributes to pathogenesis of depression, and to examine potential mechanisms by which IL-6 affects mood and cognition. A secondary objective is to compare depressed participants with and without evidence of low-grade systemic inflammation.
•Age between 20-65 years
•Diagnosis of depression
Lead Researcher and Organisation: Golam Khandaker, Cambridgeshire and Peterborough NHS Foundation Trust and The University of Cambridge
Purpose/Long-title of study: Prevalence of neuronal cell surface antibodies in patients with psychotic illnessThe aim of the PPiP2 study is to assess the number of patients suffering from psychosis that also have anti-neuronal membrane antibodies which might be causing their illness.
•Experiencing a current episode of psychosis lasting less than 2 years. This can be a first episode or relapse
• Aged between 18-70 years
Lead Researcher and Organisation: Dr Belinda Lennox, University of Oxford
Contact if you are interested in learning more: email@example.com (Norfolk and Suffolk only)http://sinapps.org.uk/get-involved/4593748724 (National Details)
Purpose/Long-title of study: Molecular genetics of adverse drug reactions: from candidate genes to genome wide association studies.
•Aged over 18
•Must have been diagnosed with an adverse reaction to Clozapine.
Lead Researcher and Organisation: Professor Munir Pirmohamed, University of Liverpool